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ssf

Overview

Field Value
Format key ssf
Spec file formats/ssf.json
Cite name GWAS-SSF v0.1
Version 20230328
Source https://www.ebi.ac.uk/gwas/docs/summary-statistics-format
Citation Hayhurst, J., Buniello, A., Harris, L., Mosaku, A., Chang, C., Gignoux, C. R., ... & Barroso, I. (2022). A community driven GWAS summary statistics standard. bioRxiv.
## File layout
Field Value
Separator TAB
NA value #NA
Column order chromosome, base_pair_location, effect_allele, other_allele, beta, odds_ratio, hazard_ratio, standard_error, effect_allele_frequency, p_value, neg_log_10_p_value, ci_upper, ci_lower, rsid, variant_id, info, ref_allele, n
## Column mapping
Raw header Canonical
base_pair_location POS
beta BETA
chromosome CHR
ci_lower OR_95L
ci_upper OR_95U
effect_allele EA
effect_allele_frequency EAF
hazard_ratio HR
info INFO
n N
neg_log_10_p_value MLOG10P
odds_ratio OR
other_allele NEA
p_value P
ref_allele REF
rsid rsID
standard_error SE
variant_id SNPID
## Coverage

9/9 tier groups satisfied.

Tier Status Matched Missing
Variant ID yes SNPID, rsID
Genomic location yes CHR, POS
Effect / other allele yes EA, NEA
Effect size yes BETA, OR, HR Z
Uncertainty yes SE
P-value yes P, MLOG10P
Sample size yes N N_CASE
Allele frequency yes EAF MAF, NEAF
Imputation / QC yes INFO
## See also