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saige

Overview

Field Value
Format key saige
Spec file formats/saige.json
Cite name SAIGE
Version v1.1.3
Last checked 20220806
Source https://saigegit.github.io/SAIGE-doc/docs/single_step2.html
GitHub https://github.com/weizhouUMICH/SAIGE
Citation Zhou, W., Nielsen, J. B., Fritsche, L. G., Dey, R., Gabrielsen, M. E., Wolford, B. N., ... & Lee, S. (2018). Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. Nature genetics, 50(9), 1335-1341.
## Column mapping
Raw header Canonical
AF_Allele2 EAF
Allele1 NEA
Allele2 EA
BETA BETA
CHR CHR
imputationInfo INFO
N N
p.value P
POS POS
SE SE
SNPID SNPID
## Coverage

9/9 tier groups satisfied.

Tier Status Matched Missing
Variant ID yes SNPID rsID
Genomic location yes CHR, POS
Effect / other allele yes EA, NEA
Effect size yes BETA OR, HR, Z
Uncertainty yes SE
P-value yes P MLOG10P
Sample size yes N N_CASE
Allele frequency yes EAF MAF, NEAF
Imputation / QC yes INFO
## See also