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.assoc

Case/control basic allelic test from --assoc (not --linear/--logistic). Default columns; 'counts' replaces F_A/F_U with C_A/C_U; --ci 0.xy appends SE, L_xy, U_xy after OR.

Overview

Field Value
Format key plink_assoc
Spec file formats/plink_assoc.json
Cite name PLINK 1.9
Version PLINK 1.9 (doc revision 19 Aug 2025)
Last checked 20260326
Source https://www.cog-genomics.org/plink/1.9/formats#assoc
Citation Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A., Bender, D., ... & Sham, P. C. (2007). PLINK: a tool set for whole-genome association and population-based linkage analyses. The American journal of human genetics, 81(3), 559-575.
## File layout
Field Value
Separator TAB
Header row yes
Column order CHR, SNP, BP, A1, F_A, F_U, A2, CHISQ, P, OR, SE, L95, U95
## Column mapping
Raw header Canonical Canonical (secondary)
A1 EA —
A2 NEA —
BP POS —
C_A — —
C_U — —
CHISQ CHISQ —
CHR CHR —
F_A EAF_CASE —
F_U EAF_CONTROL —
L95 OR_95L —
OR OR —
P P —
SE SE —
SNP SNPID rsID
U95 OR_95U —
## Header descriptions
Column Description
A1 Allele 1 (usually minor)
A2 Allele 2 (usually major)
BP Base-pair coordinate (1-based)
C_A Allele 1 count among cases ('counts' modifier)
C_U Allele 1 count among controls ('counts' modifier)
CHISQ Allelic test chi-square (omitted with fisher / fisher-midp)
CHR Chromosome code
F_A Allele 1 frequency among cases
F_U Allele 1 frequency among controls
L95 Lower end of symmetric approx. CI for OR (--ci)
OR odds(A1|case) / odds(A1|control)
P Allelic test p-value
SE Standard error of odds ratio estimate (--ci)
SNP Variant identifier
U95 Upper end of symmetric approx. CI for OR (--ci)
## Coverage

6/9 tier groups satisfied.

Tier Status Matched Missing
Variant ID yes SNPID, rsID —
Genomic location yes CHR, POS —
Effect / other allele yes EA, NEA —
Effect size yes OR BETA, HR, Z
Uncertainty yes SE —
P-value yes P MLOG10P
Sample size no — N, N_CASE
Allele frequency no — EAF, MAF, NEAF
Imputation / QC no — INFO
## See also