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Pan-Omics

Definition
AI-generated

Pan-omics denotes study designs or analytic frameworks that span the major molecular domains—commonly genome, transcriptome, proteome, metabolome, epigenome, and sometimes microbiome—with the goal of comprehensive, integrated representation of molecular state.

Topics
Sequencing and omics tech
Synonyms
Panomics (informal)
Related
Epigenome Exposome Genome-Wide Association Study (GWAS)

Why it matters in GWAS

Pan-omic or multi-layer QTL mapping and pathway models connect GWAS hits to intermediate phenotypes, prioritize causal genes, and contextualize signals with exposome-sensitive layers (e.g. metabolome, methylome). Harmonizing assays, batch effects, and sample availability across layers is the main design constraint.

Example usage

"The pan-omics baseline included WGS, RNA-seq, plasma proteomics, and untargeted metabolomics on the same participants."

Epigenome Exposome Genome-Wide Association Study (GWAS) Genomics Metabolome Microbiome Multi-Omics Proteome Transcriptome
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Hasin Y, Seldin M, Lusis A. (2017). Multi-omics approaches to disease. Genome Biol.
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