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Transcriptome

Definition
AI-generated

The transcriptome is the complete set of RNA transcripts in a cell, tissue, or biosample at a given time, including protein-coding mRNAs and noncoding RNAs as profiled by RNA-seq, microarrays, or single-cell methods.

Topics
Sequencing and omics tech
Related
Expression Quantitative Trait Locus (eQTL) Genomics RNA Sequencing (RNA-seq)

Why it matters in GWAS

Transcriptome measurements power eQTL mapping, TWAS, and splicing analyses that connect noncoding GWAS variants to altered gene expression programs in relevant contexts.

Example usage

"Functional interpretation integrated Transcriptome evidence with GWAS signals in relevant cell states."

Expression Quantitative Trait Locus (eQTL) Genomics RNA Sequencing (RNA-seq) Splicing Quantitative Trait Locus (sQTL) Transcript Assembly Transcriptomics Transcriptome-Wide Association Study (TWAS)
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • GTEx Consortium. (2020). The GTEx Consortium atlas of genetic regulatory effects across human tissues. Science.
← Transcription Start Site (TSS) Transcriptomics →

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