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Proteome

Definition
AI-generated

The proteome is the complete set of proteins—and their isoforms and modifications—present in a cell, biofluid, or tissue, often measured by mass spectrometry or affinity-based assays.

Topics
Sequencing and omics tech
Related
Genomics Multi-Omics Protein Quantitative Trait Locus (pQTL)

Why it matters in GWAS

Protein levels sit downstream of transcription and translation; pQTL mapping and proteomic GWAS help test whether expression-associated variants propagate to the proteome and can clarify druggable targets.

Example usage

"The methods explicitly include Proteome to support interpretation of the main findings."

Genomics Multi-Omics Protein Quantitative Trait Locus (pQTL) Proteomics Transcriptome
Related-term network

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References

  • Emilsson V, et al. (2018). Co-regulatory networks of human serum proteins link genetics to disease. Science.
← Protein-truncating variant (PTV) Proteomics →

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