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Genome

Definition
AI-generated

A genome is the complete set of genetic material of an organism—typically all nuclear chromosomes plus, when relevant, organellar DNA—represented as DNA sequence and its organization.

Topics
Core genetics
Related
Genetics Genome Annotation Genome Coordinate System

Why it matters in GWAS

GWAS scan variation across the genome (or a large fraction of it) to find loci associated with traits; imputation, annotation, and fine-mapping all assume a reference genome assembly and coordinates.

Example usage

"At this locus, Genome annotations were used to prioritize plausible biological mechanisms."

Genetics Genome Annotation Genome Coordinate System Genome-Wide Association Study (GWAS) Genomics Whole-Genome Sequencing (WGS)
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Alberts B, et al. (2015). Molecular Biology of the Cell. Garland Science.
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