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Genomics

Definition
AI-generated

Genomics is the large-scale study of genomes—their sequence, variation, structure, regulation, and evolution—typically using high-throughput sequencing and computational analysis across many loci simultaneously.

Why it matters in GWAS

GWAS is a central genomics application: genome-wide genotyping or sequencing plus statistical association links DNA variation to traits at scale, often integrated with other omics layers.

Example usage

"Our genomics core processed array data for 500,000 participants before imputation to the TOPMed panel."

References

  • Green ED, Watson JD, Collins FS. (2015). Human Genome Project: Twenty-five years of big biology. Nature.

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