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Phylogeny

Definition
AI-generated

A phylogeny is an inferred evolutionary tree (or network) relating taxa or sequences, with branches representing descent from common ancestors and lengths often reflecting time or sequence divergence.

Topics
Evolutionary genetics
Related
Common Ancestor Genetic Divergence Homology

Why it matters in GWAS

Phylogenies support orthology assignment, conservation scoring, and zoonotic or pathogen context for immune loci; some fine-mapping and annotation pipelines use mammalian phylogenetic shadowing or multispecies alignments to prioritize variants.

Example usage

"The methods explicitly include Phylogeny to support interpretation of the main findings."

Common Ancestor Genetic Divergence Homology Ortholog Paralog Speciation
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Felsenstein J. (2004). Inferring Phylogenies. Sinauer Associates.
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