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Browser Extensible Data (BED)

Definition
AI-generated

BED is a tab-delimited interval format from UCSC for representing genomic regions such as peaks, genes, or custom annotation tracks.

Why it matters in GWAS

GWAS fine-mapping and annotation workflows frequently intersect variants with BED intervals (for example enhancers or open chromatin), so coordinate conventions and genome build matching are essential.

Example usage

"Credible-set variants were overlapped with ATAC-seq BED peaks to prioritize functional loci."

References

  • UCSC Genome Browser. BED format FAQ. https://genome.ucsc.edu/FAQ/FAQformat.html#format1

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