Measure of Effect¶
Definition
AI-generated
In genetic association, effect measures link genotype to phenotype: regression coefficients for quantitative traits; odds ratios in logistic case-control models; relative risk in cohort designs; hazard ratios in time-to-event analyses.
Topics
Why it matters in GWAS¶
Summary statistic formats and meta-analysis require consistent effect direction (effect allele) and scale; OR approximates RR only when disease risk is low, and time-to-event models add censoring-specific interpretation.
Example usage¶
"Downstream interpretation uses Measure of Effect to link statistical findings to biological context."
Related terms¶
References¶
- GWASTutorial: Measure of effect.
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