Skip to content

Effect Size

Definition
AI-generated

Effect size is the magnitude of association between genotype and trait.

Topics
Probability and inference
Related
Additive Genetic Model Effect Allele Odds Ratio (OR)

Why it matters in GWAS

Accurate effect sizes feed PRS, MR, and power planning; selection on significance (winner's curse) biases reported magnitudes for top hits.

Example usage

"Results report Effect Size to quantify signal strength and uncertainty alongside p-values."

Additive Genetic Model Effect Allele Odds Ratio (OR) Winner's curse Measure of effect
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Winkler TW, et al. (2014). Quality control and conduct of genome-wide association meta-analyses. Nat Protoc.
← Effect Allele Effective population size (Ne) →

Last updated (UTC · Git history)