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Mean Squared Error (MSE)

Definition
AI-generated

The mean squared error (MSE) averages squared residuals: (1/n) Σ (yᵢ − ŷᵢ)².

Synonyms

Why it matters in GWAS

MSE is a standard metric for continuous trait prediction, dosage or imputation error, and residual variance in polygenic models; compare against null models and report scale so improvements are interpretable (e.g. same units as the phenotype).

Example usage

"The CNN baseline lowered MSE for predicted expression compared with elastic net in held-out GTEx tissues."

References

  • Hastie T, Tibshirani R, Friedman J. (2009). The Elements of Statistical Learning. Springer.

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