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Informed Consent

Definition
AI-generated

Informed consent is the process by which a person voluntarily agrees to participate in research or clinical care after disclosure of material information—purpose, risks, benefits, alternatives, confidentiality, and rights such as withdrawal—at a level appropriate to the context.

Topics
Ethics, law & society
Related
All of Us Biobank Electronic Health Records (EHRs)

Why it matters in GWAS

Broad genomic research often uses tiered or dynamic consent (e.g. return of results, data sharing, commercial use); mismatch between consent scope and secondary analyses (including biobank linkage to EHRs) creates ethical and legal risk and can undermine participant trust.

Example usage

"The protocol amendment required renewed informed consent before linking genotypes to pharmacy claims."

All of Us Biobank Electronic Health Records (EHRs) Genetic Privacy Genome-Wide Association Study (GWAS) Institutional Review Board (IRB)
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Grady C. (2015). Enduring and emerging challenges of informed consent. N Engl J Med.
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