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Spearman rank correlation coefficient

Definition
AI-generated

Monotonic rank-based correlation; robust to heavy tails in omics traits.

Why it matters in GWAS

Statistical concepts underpin GWAS significance, effect estimation, relatedness random effects, multiple testing, fine-mapping priors, and post-GWAS multivariate methods.

Example usage

"A replication analysis checks whether assumptions tied to Spearman rank correlation coefficient remain stable across cohorts."

References

  • Casella G, Berger RL. (2002). Statistical Inference. Duxbury Press.
  • Wasserman L. (2004). All of Statistics. Springer.

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