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Statistical Power

Definition
AI-generated

Statistical power is the probability that a test rejects the null when it is false (1 minus Type II error rate).

Why it matters in GWAS

Underpowered studies miss true associations; understanding power guides cohort design, replication, and interpretation of null results at a given sample size.

Example usage

"The analysis uses Statistical Power to quantify associations and compare alternative hypotheses."

References

  • Sham PC, Purcell SM. (2014). Statistical power and significance testing in large-scale genetic studies. Nat Rev Genet.
  • GWASTutorial: Power analysis for GWAS.

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