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Likelihood

Definition
AI-generated

Function of parameters given observed data proportional to data probability—maximized in MLE and used in Bayes numerators.

Why it matters in GWAS

Statistical concepts underpin GWAS significance, effect estimation, relatedness random effects, multiple testing, fine-mapping priors, and post-GWAS multivariate methods.

Example usage

"The analysis framework includes Likelihood to quantify evidence and compare competing hypotheses."

References

  • Casella G, Berger RL. (2002). Statistical Inference. Duxbury Press.
  • Wasserman L. (2004). All of Statistics. Springer.

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