Skip to content

LiftOver

Definition
AI-generated

LiftOver converts genomic coordinates between reference assemblies (for example GRCh37/hg19 to GRCh38/hg38) using alignment chain files, via UCSC's liftOver tool or equivalent APIs.

Topics
Post-GWAS
Related
Genome-Wide Association Study (GWAS) Fine-Mapping

Why it matters in GWAS

Meta-analysis, annotation, and colocalization require a single build; mismatched positions cause missed overlap with LD reference panels or eQTL catalogs.

Example usage

"A replication step checks whether LiftOver assumptions remain stable across cohorts."

Genome-Wide Association Study (GWAS) Fine-Mapping
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

← LiftOff Likelihood →

Last updated (UTC · Git history)