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Codominant model

Definition
AI-generated

In association testing, a parameterization where heterozygotes have their own mean distinct from either homozygote class.

Topics
Core genetics
Related
Additive Genetic Model Dominant Genetic Model Recessive Genetic Model

Why it matters in GWAS

These concepts shape how we expect variants to act (penetrance, heterogeneity, threshold models) and how GWAS signals should be interpreted alongside family-based evidence.

Example usage

"A codominant model estimated separate effects for heterozygous and homozygous genotypes at the lead variant."

Additive Genetic Model Dominant Genetic Model Recessive Genetic Model
Related-term network

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Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.
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