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Base Pair (bp)

Definition
AI-generated

A base pair (bp) is one rung of the DNA double helix: a hydrogen-bonded pair of nucleotides (A–T or G–C) on opposite strands.

Topics
Molecular biology
Related
Genome Coordinate System Liftover Reference Allele

Why it matters in GWAS

Association summaries and reference builds specify positions in bp; window sizes for LD, fine-mapping, and liftover all depend on consistent bp coordinates and genome assembly.

Example usage

"The lead enhancer lies about 12 kb upstream—roughly 12,000 base pair positions from the transcription start site."

Genome Coordinate System Liftover Reference Allele Single Nucleotide Polymorphism (SNP) Variant Annotation
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Schneider VA, et al. (2017). Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly. Genome Res.
← Base calling Base quality →

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