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SMRT sequencing

Definition
AI-generated

Single Molecule Real-Time sequencing on zero-mode waveguides producing long reads with native molecule context (methylation on some platforms).

Topics
Sequencing and omics tech
Related
Hifi Sequencing Pacbio Sequencing Long Read Sequencing

Why it matters in GWAS

Bioinformatics methods determine how variants, expression, and epigenetic state are measured and summarized—shaping GWAS covariates, multi-omic integration, and functional follow-up.

Example usage

"Quality-controlled SMRT sequencing data were used to prioritize robust loci and downstream functional follow-up."

Hifi Sequencing Pacbio Sequencing Long Read Sequencing
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Lesk AM. (2019). Introduction to Bioinformatics. Oxford University Press.
← SMART-seq Single Nucleotide Polymorphism (SNP) →

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