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SMART-seq

Definition
AI-generated

Single-cell full-length cDNA protocol using template switching for mRNA-seq from individual cells—historically common for scRNA workflows.

Why it matters in GWAS

Bioinformatics methods determine how variants, expression, and epigenetic state are measured and summarized—shaping GWAS covariates, multi-omic integration, and functional follow-up.

Example usage

"Quality-controlled SMART-seq data were used to prioritize robust loci and downstream functional follow-up."

References

  • Lesk AM. (2019). Introduction to Bioinformatics. Oxford University Press.

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