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Single-end sequencing

Definition
AI-generated

Sequencing reads from one fragment end only—cheaper but less accurate indel and insert resolution than paired-end.

Topics
Sequencing and omics tech
Related
Paired End Sequencing Short Read Sequencing Read Depth

Why it matters in GWAS

Bioinformatics methods determine how variants, expression, and epigenetic state are measured and summarized—shaping GWAS covariates, multi-omic integration, and functional follow-up.

Example usage

"Quality-controlled Single-end sequencing data were used to prioritize robust loci and downstream functional follow-up."

Paired End Sequencing Short Read Sequencing Read Depth
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Lesk AM. (2019). Introduction to Bioinformatics. Oxford University Press.
← Single-Cell Sequencing Single-nucleus RNA sequencing (snRNA-seq) →

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