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Posterior distribution

Definition
AI-generated

Distribution of parameters after conditioning on observed data; underlies credible intervals in Bayesian fine-mapping.

Why it matters in GWAS

Statistical concepts underpin GWAS significance, effect estimation, relatedness random effects, multiple testing, fine-mapping priors, and post-GWAS multivariate methods.

Example usage

"The statistical workflow uses Posterior distribution to evaluate evidence strength and calibration under multiple testing."

References

  • Casella G, Berger RL. (2002). Statistical Inference. Duxbury Press.
  • Wasserman L. (2004). All of Statistics. Springer.

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