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Mean Absolute Error (MAE)

Definition
AI-generated

The mean absolute error (MAE) averages absolute differences between predicted and observed values: (1/n) Σ |yᵢ − ŷᵢ|.

Synonyms

Why it matters in GWAS

MAE summarizes error for polygenic prediction of quantitative traits (e.g. BMI, lipids), imputation quality panels, or embedding regression; compare against the scale and naive baselines (mean predictor) when judging gains from genetic predictors.

Example usage

"The linear PRS reduced MAE for HDL by 0.08 mmol/L versus age and sex alone in the external cohort."

References

  • Willmott CJ, Matsuura K. (2005). Advantages of the mean absolute error (MAE) over the root mean square error (RMSE). Clim Res.

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