Lipidomics¶
Definition
AI-generated
Lipidomics is the systematic measurement and analysis of lipid molecules and their distributions across pathways, often integrated with genetics as lipidome-wide association studies.
Topics
Why it matters in GWAS¶
Lipidomics connects cardiovascular and metabolic GWAS loci to specific molecular lipid intermediates, helping distinguish lipoprotein particle effects from enzymatic steps in fatty acid metabolism.
Example usage¶
"Lipidomics GWAS highlighted variants near elongase genes affecting very-long-chain ceramides."
Related terms¶
References¶
- Ahrends R, et al. (2019). Lipidomics in health and disease—subtle differences with dramatic impact. Nat Rev Endocrinol.
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