Identity by State (IBS)¶
Definition
AI-generated
Two alleles are identical by state (IBS) if they have the same nucleotide (or same coded genotype) at a marker, regardless of whether they were inherited from a common ancestor.
Topics
Why it matters in GWAS¶
Relationship algorithms (e.g. PLINK/KING) use IBS allele-sharing proportions to estimate kinship; high IBS can reflect relatedness or, at a single SNP, chance agreement for common alleles.
Example usage¶
"The methods include Identity by State (IBS) to support interpretation of the main results."
Related terms¶
References¶
- GWASTutorial: Relatedness and sample structure.
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