Skip to content

IBS0

Definition
AI-generated

IBS0 is the proportion of markers at which two individuals share zero alleles identical by state.

Why it matters in GWAS

IBS0 complements kinship or PI_HAT estimates during QC because close relationships can have similar overall sharing but different IBS0 patterns.

Example usage

"The pair had near-zero IBS0, which supported a parent-offspring relationship rather than full siblings."

References

  • Manichaikul A, et al. (2010). Robust relationship inference in genome-wide association studies. Bioinformatics.

Last updated (UTC · Git history)