IBS0¶
Definition
AI-generated
IBS0 is the proportion of markers at which two individuals share zero alleles identical by state.
Topics
Why it matters in GWAS¶
IBS0 complements kinship or PI_HAT estimates during QC because close relationships can have similar overall sharing but different IBS0 patterns.
Example usage¶
"The pair had near-zero IBS0, which supported a parent-offspring relationship rather than full siblings."
Related terms¶
References¶
- Manichaikul A, et al. (2010). Robust relationship inference in genome-wide association studies. Bioinformatics.
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