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Allele Sharing

Definition
AI-generated

Allele sharing describes the extent to which two individuals carry the same alleles at one locus or across many loci.

Topics
Core genetics
Related
IBS0 Identity by Descent (IBD) Identity by State (IBS)

Why it matters in GWAS

Allele-sharing patterns underpin kinship estimation, duplicate detection, and relationship inference in sample QC pipelines.

Example usage

"Unexpected allele sharing between the samples prompted a duplicate check."

IBS0 Identity by Descent (IBD) Identity by State (IBS) Relatedness
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Manichaikul A, et al. (2010). Robust relationship inference in genome-wide association studies. Bioinformatics.
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