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Homologous

Definition
AI-generated

Homologous describes chromosomes that pair in meiosis, or genes and sequences that share homology—descent from a common ancestor rather than similarity alone.

Topics
Evolutionary genetics
Related
Homology Homolog Meiosis

Why it matters in GWAS

Analysts distinguish homologous loci across species or within gene families when interpreting conservation and when mapping results onto model organisms.

Example usage

"The regulatory SNP lay in a region homologous to a conserved mouse enhancer."

Homology Homolog Meiosis
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Hartl DL, Clark AG. (2007). Principles of Population Genetics. Sinauer Associates.
  • Jobling MA, Hurles ME, Tyler-Smith C. (2013). Human Evolutionary Genetics. Garland Science.
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