Skip to content

Hi-C

Definition
AI-generated

Genome-wide chromosome conformation capture with unbiased ligation and sequencing inferring A/B compartments, TADs, and long-range loops.

Topics
Sequencing and omics tech
Related
Chromosome Conformation Capture 3C Chromatin Enhancer

Why it matters in GWAS

Bioinformatics methods determine how variants, expression, and epigenetic state are measured and summarized—shaping GWAS covariates, multi-omic integration, and functional follow-up.

Example usage

"A replication analysis checks whether Hi-C assumptions hold across cohorts."

Chromosome Conformation Capture 3C Chromatin Enhancer
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Lesk AM. (2019). Introduction to Bioinformatics. Oxford University Press.
← Heuristic Hidden Markov model (HMM) →

Last updated (UTC · Git history)