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Coefficient of Relationship

Definition
AI-generated

The coefficient of relationship is the probability that an allele chosen at random from one individual is identical by descent (IBD) to an allele at the same locus in another—the same quantity many papers denote r.

Topics
Population genetics
Related
Coefficient of relatedness (r) Identity by Descent (IBD) Kinship Coefficient

Why it matters in GWAS

Relationship coefficients set expectations for kinship filters, cryptic relatedness, and family-based designs.

Example usage

"The pedigree implied a coefficient of relationship of 0.5 between the duplicated samples."

Coefficient of relatedness (r) Identity by Descent (IBD) Kinship Coefficient Relatedness Coefficient
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Thompson EA. (2013). Identity by descent: variation in meiosis, across genomes, and in populations. Genetics.
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