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Antisense strand

Definition
AI-generated

Template DNA strand read 3′→5′ to synthesize RNA opposite in polarity to the resulting transcript.

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"Primer design referenced the antisense strand coordinates to ensure correct orientation for targeted transcript quantification."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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