Apoptosis¶
Definition
AI-generated
Programmed cell death executed by intracellular pathways; relevant to tissue homeostasis and some disease mechanisms.
Topics
Why it matters in GWAS¶
GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.
Example usage¶
"Risk-allele carriers showed higher caspase-3 activity after oxidative stress, consistent with increased apoptosis sensitivity."
Related terms¶
References¶
- Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.
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