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Sense strand

Definition
AI-generated

DNA strand with the same 5′→3′ polarity as the mature RNA transcript (non-template coding orientation).

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"The methods section includes Sense strand to support interpretation of the primary findings."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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