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Zygosity

Definition
AI-generated

Zygosity describes whether an individual’s two copies at a locus are the same (homozygosity) or different (heterozygosity), or whether only one copy is present (hemizygosity).

Topics
Core genetics
Related
Genotype Compound Heterozygote Hemizygote

Why it matters in GWAS

Correct zygosity calls underpin genotype dose, HWE checks, and dominance/recessive models; global outlier heterozygosity flags sample problems (contamination, swaps, inbreeding).

Example usage

"Per-SNP zygosity counts feed the exact HWE test; sample-level zygosity rate flagged two outliers."

Genotype Compound Heterozygote Hemizygote Heterozygote Heterozygosity Homozygote Hardy-Weinberg Equilibrium (HWE)
Related-term network

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Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

← Z test Zygote →

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