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T cell receptor sequencing (TCR-seq)

Definition
AI-generated

Sequencing rearranged TCR chains to profile clonal diversity and antigen-experienced compartments—used in tumor and infection companion studies.

Topics
Sequencing and omics tech
Related
B Cell Receptor Sequencing Single Cell Sequencing

Why it matters in GWAS

Bioinformatics methods determine how variants, expression, and epigenetic state are measured and summarized—shaping GWAS covariates, multi-omic integration, and functional follow-up.

Example usage

"Quality-controlled T cell receptor sequencing (TCR-seq) data were used to prioritize robust loci and downstream functional follow-up."

B Cell Receptor Sequencing Single Cell Sequencing
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Lesk AM. (2019). Introduction to Bioinformatics. Oxford University Press.
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