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Structural equation modeling (SEM)

Definition
AI-generated

Joint system of measurement and structural equations—distinct from abbreviation clashes with “standard error mean.”

Why it matters in GWAS

Statistical concepts underpin GWAS significance, effect estimation, relatedness random effects, multiple testing, fine-mapping priors, and post-GWAS multivariate methods.

Example usage

"The analysis uses Structural equation modeling (SEM) to quantify associations and compare alternative hypotheses."

References

  • Casella G, Berger RL. (2002). Statistical Inference. Duxbury Press.
  • Wasserman L. (2004). All of Statistics. Springer.

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