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Phred quality score

Definition
AI-generated

A Phred quality score Q means an error probability of 10^(−Q/10).

Synonyms

Why it matters in GWAS

Phred scaling unifies QC thresholds across tools; miscalibrated scores undermine filters and association tests.

Example usage

"A Phred quality score of Q30 implies roughly one base error per thousand calls under ideal calibration."

References

  • Ewing B, Green P. (1998). Base-calling of automated sequencer traces using phred. II. Error probabilities. Genome Res.

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