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Non-risk Allele

Definition
AI-generated

A non-risk allele is the allele at a variant that is not associated with increased risk for the specified phenotype in the stated analysis context.

Topics
Core genetics GWAS
Related
Risk Allele Effect Allele Non-effect Allele

Why it matters in GWAS

This label is relative to a specific trait, model, and population. In one analysis it may be "protective" (opposite direction of risk), while in another context the direction or interpretation can change.

Example usage

"Relative to the risk allele, the non-risk allele showed lower disease odds in the replication study."

Risk Allele Effect Allele Non-effect Allele Odds Ratio Reference Allele
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

← Non-homologous end joining (NHEJ) Noncoding Variant →

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