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Narrow-Sense Heritability

Definition
AI-generated

Narrow-sense heritability is the proportion of phenotypic variance attributable to additive genetic effects alone.

Topics
Core genetics
Related
Broad-Sense Heritability Heritability Missing Heritability

Why it matters in GWAS

Additive effects are the component most commonly estimated from unrelated individuals and SNP data, making narrow-sense heritability central to interpretation of GWAS yield and polygenic prediction.

Example usage

"We compared the SNP-based estimate to published narrow-sense heritability from family studies."

Broad-Sense Heritability Heritability Missing Heritability SNP Heritability
Related-term network

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References

  • Visscher PM, Hill WG, Wray NR. (2008). Heritability in the genomics era. Nat Rev Genet.
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