Multi-ancestry¶
Definition
AI-generated
Designs or samples including several ancestries with explicit proportional or structured representation.
Topics
Why it matters in GWAS¶
Population structure, demographic history, and mating patterns affect allele frequencies, LD, relatedness, and cross-cohort portability—central to GWAS design and interpretation.
Example usage¶
"Multi-ancestry estimates were incorporated to improve portability and calibration across diverse cohorts."
Related terms¶
References¶
- Hartl DL, Clark AG. (2007). Principles of Population Genetics. Sinauer Associates.
- Jobling MA, Hurles ME, Tyler-Smith C. (2013). Human Evolutionary Genetics. Garland Science.
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