Skip to content

Molecular Diagnostics

Definition
AI-generated

Molecular diagnostics detect or quantify nucleic acids, proteins, or other molecular analytes to inform disease classification, infection, pharmacogenomics, or monitoring—spanning PCR, hybridization, sequencing, and multiplex panels.

Topics
Precision medicine
Related
Biomarker Companion Diagnostics Genome-Wide Association Study (GWAS)

Why it matters in GWAS

Association studies depend on consistent molecular measurement (genotyping, imputation, WGS quality) and on phenotypes that may be defined by diagnostic labels derived from molecular tests; pharmacogenomic GWAS links germline variation to drug response phenotypes that laboratories later operationalize as assays.

Example usage

"Molecular diagnostics confirmed the pharmacogenomic allele before starting the high-risk drug."

Biomarker Companion Diagnostics Genome-Wide Association Study (GWAS) Precision Medicine Whole-Genome Sequencing (WGS)
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Grody WW, et al. (2008). ACMG statement on laboratory diagnosis of molecular genetic diseases. Genet Med.
← Modifier variant Monoallelic →

Last updated (UTC · Git history)