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Polymerase chain reaction (PCR)

Definition
AI-generated

Enzymatic amplification of a DNA target between primers; basis of many genotyping and sequencing prep workflows.

Topics
Molecular biology
Related
PCR amplification Primer Genotyping Array

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"A replication analysis checks whether assumptions tied to Polymerase chain reaction (PCR) hold across cohorts."

PCR amplification Primer Genotyping Array Short Read Sequencing
Related-term network

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Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.
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