Leave-one-out cross-validation¶
Definition
AI-generated
Extreme k-fold where each observation serves once as its own validation fold—expensive but nearly unbiased in small n.
Topics
Why it matters in GWAS¶
Statistical concepts underpin GWAS significance, effect estimation, relatedness random effects, multiple testing, fine-mapping priors, and post-GWAS multivariate methods.
Example usage¶
"A replication step checks whether Leave-one-out cross-validation assumptions remain stable across cohorts."
Related terms¶
References¶
- Casella G, Berger RL. (2002). Statistical Inference. Duxbury Press.
- Wasserman L. (2004). All of Statistics. Springer.
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