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Large Language Model (LLM)

Definition
AI-generated

A large language model is a neural network trained on vast text to predict the next token (or span), typically using a transformer architecture; at scale it can generate fluent prose, summarize documents, translate, and follow instructions, with capabilities that depend on architecture, data, and alignment training.

Synonyms

Why it matters in GWAS

LLMs are increasingly used to draft methods text, parse nomenclature, suggest code, and triage literature—but outputs must be verified against primary data, statistics, and curated databases because models can be outdated or confidently wrong.

Example usage

"We used an LLM to draft a first-pass plain-language summary of the GWAS loci, then edited against the supplementary tables."

References

  • Brown T, et al. (2020). Language models are few-shot learners. NeurIPS.
  • Bommasani R, et al. (2021). On the opportunities and risks of foundation models. arXiv:2108.07258.

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