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Introgressive hybridization

Definition
AI-generated

Admixture transferring alleles across species boundaries via backcrossing—stronger emphasis than generic introgression.

Why it matters in GWAS

Population structure, demographic history, and mating patterns affect allele frequencies, LD, relatedness, and cross-cohort portability—central to GWAS design and interpretation.

Example usage

"Introgressive hybridization is referenced when translating statistical signals into biological context."

References

  • Hartl DL, Clark AG. (2007). Principles of Population Genetics. Sinauer Associates.
  • Jobling MA, Hurles ME, Tyler-Smith C. (2013). Human Evolutionary Genetics. Garland Science.

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