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Histone

Definition
AI-generated

Nuclear proteins forming the octamer core of nucleosomes around which DNA wraps.

Topics
Molecular biology
Related
Nucleosome Chromatin Dna Methylation

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"Functional assays used Histone context to connect noncoding variants with regulatory effects."

Nucleosome Chromatin Dna Methylation
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.
← Hispanic or Latino Histone modification →

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