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Histone modification

Definition
AI-generated

Post-translational marks on histone tails (methylation, acetylation, etc.) read by chromatin machinery.

Topics
Molecular biology
Related
Histone Acetylation Methylation

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"Functional assays used Histone modification context to connect noncoding variants with regulatory effects."

Histone Acetylation Methylation
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.
← Histone HLA Region →

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