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Fixation index

Definition
AI-generated

Fixation index most often means a measure of allele-frequency differentiation between groups; in GWAS and population genetics that is usually F_ST.

Topics
Population genetics
Related
F-Statistics Fixation index (FST) Population Stratification

Why it matters in GWAS

The same symbol and phrase appear in methods reporting population structure, stratification checks, and cross-ancestry comparisons—use a precise estimator and cite it.

Example usage

"Downstream interpretation uses Fixation index to contextualize the main association signal."

F-Statistics Fixation index (FST) Population Stratification
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Wright S. (1951). The genetical structure of populations. Ann Eugen.
  • Weir BS, Cockerham CC. (1984). Estimating F-statistics for the analysis of population structure. Evolution.
← Fixation Foundation Model →

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